The culture of Diriamba, a synthesis of Spanish and Amerindians cultures combining theatre, dance and music, is considered one of Latin America’s most distinctive colonial-era expressions.

The popular and traditional culture of Diriamba is proclaimed by the religious spirit of its people during the celebration of the feast of San Sebastian, patron saint of the city. The feast takes place from 17 to 27 January; being the 19th, the 20th and the 27th the dates when the image is taken in street processions across the city together with the images of St. Mark and Santiago patron saints of the neighbor cities of San Marcos and Jinotepe respectively. The venerated images of San Sebastian and Santiago were brought from Spain; according to the legend the images appeared floating in the Pacific Ocean.